Kathleen F Benson Selected Research

Cyclic neutropenia

9/2007	Double de novo mutations of ELA2 in cyclic and severe congenital neutropenia.
4/2004	Hereditary neutropenia: dogs explain human neutrophil elastase mutations.
1/2004	Paradoxical homozygous expression from heterozygotes and heterozygous expression from homozygotes as a consequence of transcriptional infidelity through a polyadenine tract in the AP3B1 gene responsible for canine cyclic neutropenia.
9/2003	Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase.
1/2003	Role of neutrophil elastase in bone marrow failure syndromes: molecular genetic revival of the chalone hypothesis.
11/2002	Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis.

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Kathleen F Benson Research Topics

Disease

8	Autosomal Recessive 3 Severe Congenital Neutropenia 09/2007 - 11/2002
6	Neutropenia 08/2009 - 04/2003
6	Cyclic neutropenia 09/2007 - 11/2002
4	Inflammation (Inflammations) 01/2020 - 07/2011
3	Chronic Pain 07/2016 - 05/2012
3	Pain (Aches) 01/2015 - 07/2011
3	Leukemia 01/2006 - 02/2002
2	Neoplasms (Cancer) 03/2010 - 01/2003
1	Hypertension (High Blood Pressure) 01/2016
1	Wounds and Injuries (Trauma) 01/2016
1	Anemia 01/2014
1	Hypersensitivity (Allergy) 09/2011
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2010
1	Bone Marrow Failure Disorders 01/2003

Drug/Important Bio-Agent (IBA)

8	Leukocyte Elastase (Neutrophil Elastase)IBA 08/2009 - 11/2002
4	Proteins (Proteins, Gene)FDA Link 08/2009 - 02/2002
2	AntioxidantsIBA 11/2014 - 07/2011
2	Peptide Hydrolases (Proteases)FDA Link 09/2007 - 09/2003
2	Adaptor Protein Complex 3IBA 04/2004 - 09/2003
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	AnticoagulantsIBA 07/2016
1	Antiviral Agents (Antivirals)IBA 01/2016
1	nattokinaseIBA 01/2016
1	Histamine (Histamine Dihydrochloride)FDA Link 03/2015
1	CytokinesIBA 01/2015
1	Hyaluronic Acid (Hyaluronan)IBA 01/2015
1	PolyphenolsIBA 11/2014
1	Plant Preparations (Preparation, Plant)IBA 01/2014
1	ErgothioneineIBA 05/2012
1	Secretory Immunoglobulin A (SIgA)IBA 09/2011
1	Interleukin-8 (Interleukin 8)IBA 03/2010
1	Interleukin-10 (Interleukin 10)IBA 03/2010
1	EnzymesIBA 01/2006
1	polyadenineIBA 01/2004
1	Notch ReceptorsIBA 01/2004
1	Serine Proteases (Serine Protease)IBA 01/2004
1	Pancreatic Elastase (Elastase)IBA 04/2003

Therapy/Procedure

1	Activities of Daily Living (ADL) 07/2011
1	Therapeutics 01/2003